منابع مشابه
Atheroma progression in chronic kidney disease.
BACKGROUND AND OBJECTIVES Cardiovascular events are 10 to 100 times more frequent in chronic kidney disease (CKD). We tested the hypothesis that the rate of atherosclerotic plaque growth is faster in severe versus moderate CKD. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS We performed a prospective cohort study in 318 prevalent CKD patients with initial creatinine clearance (CCr) between 20 ...
متن کاملAtheroma progression in hyporesponders to statin therapy.
OBJECTIVE Lowering low-density lipoprotein cholesterol (LDL-C) with statins has been demonstrated to slow plaque progression. This antiatherosclerotic effect in patients with minimal LDL-C lowering has not been investigated. APPROACH AND RESULTS Six hundred forty-seven patients with angiographic coronary artery disease who were commenced on statin therapy underwent serial imaging with intrava...
متن کاملVascular oxidant stress enhances progression and angiogenesis of experimental atheroma.
BACKGROUND Although multiple pathological processes have been associated with oxidative stress, the causative relation between oxidative stress and arterial lesion progression remains unclear. METHODS AND RESULTS To test the effect of creating arterial wall oxidative stress, we compared progression of mouse carotid lesions induced by flow cessation in the wild-type (WT) versus transgenic mice...
متن کاملProgression of atheroma: a struggle between death and procreation.
Traditional thinking accorded a major role to deranged cell proliferation as a determinant of the abnormal cellularity of atheroma. However, studies conducted in several laboratories have documented the occurrence of disordered apoptosis during atherogenesis, leading to the death of lipid-rich foam cells (promoting lipid-core formation) and depletion of vascular smooth muscle cells (fostering f...
متن کاملMultivessel coronary artery disease: atheroma progression and dynamic component
Multivessel or multisegment spasm in patients with known widespread coronary atherosclerotic disease is an infrequent occurrence. We describe a prolonged spasm of both the left main and the left anterior descending artery in a patient with chronic effort angina and multivessel coronary artery disease, who previously underwent percutaneous coronary intervention and drug eluting stents implantati...
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ژورنال
عنوان ژورنال: Arteriosclerosis, Thrombosis, and Vascular Biology
سال: 2002
ISSN: 1079-5642,1524-4636
DOI: 10.1161/01.atv.0000031341.84618.a4